重新考虑下垂体微腺瘤的MRI协议:优先考虑非对比成像,以确保安全的随访
Fariba Zarei1,2, Farideh Nematollahi2, Asadolah Jalil2
1Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz 71936-35899, Iran.
概括
非对比的MRI可以可视化大多数垂体小腺瘤,排除显著的生长,并支持其在后续成像中使用. 这种方法可以降低患者使用加多对比剂的风险.
科学领域:
- 放射学 放射学是一门学科.
- 神经成像是一种神经成像.
- 在瘤学瘤学.
背景情况:
- 动态对比增强型MRI (DCE-MRI) 是垂体瘤诊断和监测的标准.
- 基于加多的对比剂 (GBCA) 携带组织保留和不良反应的风险.
- 评估随访的非对比MRI序列对于减轻这些风险至关重要.
研究的目的:
- 评估无对比度MRI (T1W/T2W) 的灵敏度,以对 pituitary microadenoma进行随访.
- 将非对比MRI检测率与DCE-MRI进行比较.
- 评估瘤的稳定性随着时间的推移而没有对比剂.
主要方法:
- 对300个下垂体MRI扫描 (2020-2024) 的回顾性审查.
- 包括确诊微腺瘤 (≤10毫米) 的患者.
- 盲目放射科医生对非对比 (T1W/T2W) 和DCE-MRI序列的分析.
主要成果:
- 检测率:T1W (55.7%),T2W (70.9%),DCE-MRI (88.6%) 在79种微腺瘤中.
- 在随访期间没有观察到显著的瘤生长 (平均尺寸为4.80 ± 2.3毫米,而不是4.81 ± 2.4毫米).
- p值>0.5表明没有统计学上显著的变化.
结论:
- 非对比的MRI可视化了大多数检测到的微腺瘤.
- 排除了显著的增长,支持稳定病例的对比缺失.
- 消除gadolinium对比度可能会降低成本和患者的风险.
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