在流行病限制后,美国中毒中心报告的海洋毒素中毒的差异
Baylin J Bennett1, Cailee Hill2,3, Hugh B Roland4
1Department of Medicine, Division of Occupational, Environmental and Climate Medicine, University of California, 490 Illinois Street, San Francisco, CA 94158, USA.
在COVID-19大流行期间,海洋毒素中毒发生了变化. 虽然一些人减少了,但毒素和四毒素中毒显著增加,四毒素与流行病限制和户外活动有关.
科学领域:
- 环境毒理学环境毒理学
- 公共卫生监督是对公共卫生的监督.
- 流行病学 流行病学
背景情况:
- 海洋毒素中毒对公众健康构成重大风险.
- 了解这些中毒的时间趋势对于预防至关重要.
- COVID-19 流行病可能影响了人类的行为,导致了毒素暴露.
研究的目的:
- 调查美国报告的海洋毒素中毒发生率的变化. 在COVID-19大流行期间的毒药中心.
- 分析特定海洋毒素的趋势,包括ciguatera,clupeotoxic鱼,腹贝类,贝类,scombroid鱼,palytoxin和tetrodotoxin.
- 确定流行病限制与中毒量观察到的变化之间的关联.
主要方法:
- 利用国家毒素数据系统查询单一物质对人类的暴露要求,从2000年到2022年查询伊氏类毒素.
- 雇佣混合效应负二项式回归来计算风险调用的发生率比率.
- 按年汇总呼叫数量,并将它们与大流行期间 (2020年4月至2021年12月) 的二进制指标进行回归.
主要成果:
- 在大流行的高峰期,对ciguatera,clupeotoxic鱼类,腹性贝类,性贝类和scombroid鱼类中毒的暴露呼叫显著下降.
- 在同一时期,毒素中毒和毒素中毒暴露电话显著增加.
- 敏感性分析表明,毒素的增加早于限制日期,而毒素的增加与限制有关,可能与增加户外活动有关.
结论:
- COVID-19 流行病改变了美国海洋毒素中毒的情况.
- 特定的毒素,如毒素和四毒素显示有关增加,需要进一步调查和有针对性的公共卫生干预措施.
- 杆毒素暴露趋势表明,与大流行期间增加户外活动的参与有关.
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