通过发酵的食物衍生乳酸细菌减轻环境Enterococcus faecalis的毒性
Mohammed Aman1, Sushma S Murthy2, Arpitha Somayaji2
1Department of Microbiology and Botany, School of Sciences, Jain (Deemed to Be University), JC Road, Bangalore, Karnataka, 560002, India. mohammed@jainuniversity.ac.in.
Current microbiology
|September 26, 2025
概括
环境Enterococcus faecalis菌株表现出高毒性和抗生素耐药性. 来自食物的益生菌,特别是Pediococcus acidilactici和Streptococcus thermophilus,有效地减少了这些毒性因素,提供了潜在的生物干预措施.
科学领域:
- 微生物学 微生物学
- 环境科学 环境科学
- 益生菌 益生菌 益生菌
背景情况:
- 菌 (Enterococcus faecalis) 是一种在环境水库中发现的格拉姆阳性细菌.
- 它表现出适应性,毒性和抗生素耐药性的增加,引起了公众健康的关注.
- 这项研究重点关注来自印度班加罗尔污水污染灌水中的环境E. faecalis分离物.
研究的目的:
- 从环境来源中分离和鉴定出毒的,抗生素耐药的Enterococcus faecalis菌株.
- 评估从发酵食品中的益生菌干预措施在减轻E. faecalis毒性因素方面的有效性.
- 探索乳酸细菌 (LAB) 作为可持续生物控制剂对抗肠球菌病原体的潜力.
主要方法:
- 从受污染的灌水中分离了八种Enterococcus菌株 (JUSS 01-03,05-07,09,10).
- 抗生素敏感性测试,细胞表面水性,自聚和生物膜形成测试.
- 使用益生菌菌株Pediococcus acidilactici (JUFF,JUFB) 和Streptococcus thermophilus (JUBM) 来评估毒性降低.
主要成果:
- 隔离品JUSS 05和JUSS 06 (E. faecalis) 显示出安培素耐药性和显著的毒性特征 (疏水性,聚合性,生物膜形成).
- 益生菌菌株,特别是JUBM和JUFF,在E. faecalis分离物中显著降低了疏水性,聚合和生物膜形成.
- S. thermophilus (JUBM) 显示出毒性因素的最大降低,而P. acidilactici (JUFF) 显示出广泛的抗生物膜活性.
结论:
- 环境E. faecalis菌株具有显著的致病潜力和抗生素耐药性.
- 来自食物的乳酸细菌 (LAB) 有效地降低了E. faecalis.的主要毒性因素.
- 益生菌是开发可持续生物干预措施对抗环境肠球菌感染的有希望的途径.
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