在水牛小牛中同时感染全身性候群病和二酸性阿斯伯吉洛症
Sumit S Kamble1, Veena R Sutar2, S D Vinay Kumar2
1Division of Bacteriology and Mycology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, 243 122, Uttar Pradesh, India.
Veterinary research communications
|September 26, 2025
概括
本案例研究详细介绍了一只年轻的Murrah水牛小牛的罕见真菌共感染,突出了免疫功能低下的新生儿的风险. 早期诊断和避免不适当的抗生素和皮质类固醇使用对于预防严重真菌感染至关重要.
科学领域:
- 兽医真菌学 兽医真菌学
- 新生儿病理学 新生儿病理学
- 传染性疾病 传染性疾病
背景情况:
- 新生小牛的真菌感染往往未被诊断出来,而且很危险,特别是在免疫力低下的个体中.
- 机会性真菌感染对正在发育免疫系统的年轻动物构成重大风险.
研究的目的:
- 在新生儿Murrah水牛小牛中报告一种罕见的系统性角膜炎和二利性阿斯伯吉洛症的同时感染病例.
- 强调诊断发现和对新生儿小牛管理的影响.
主要方法:
- 尸体解剖和对一个13天大的雌性Murrah水牛小牛的粗略检查.
- 肺部和腹部组织的组织病理学分析.
- 从 Sabouraud Dextrose Agar (SDA) 上的心脏血液,肺组织和气管抽样中培养的真菌培养物.
主要成果:
- 总体发现包括肺炎,气管伪膜和腹腔.
- 组织病理学发现真菌元素 (Candida tropicalis,Aspergillus fumigatus,Aspergillus flavus) 具有血管侵袭和死性炎症.
- 在血液和肺部中,培养证实了C. tropicalis,在气管抽样中证实了A. fumigatus和A. flavus.
结论:
- 这一案例凸显了新生婴儿未成熟免疫系统的新生小牛混合机会性真菌感染的风险.
- 不慎使用抗生素和皮质类固醇可以加剧这种感染的风险.
- 避免不当的治疗实践对于预防小牛严重的真菌共感染至关重要.
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