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全球碳烯酶生成菌 Serratia spp. 的分子流行病学 (2015年至2017年) 的时间

Gisele Peirano^1,2, Yasufumi Matsumura³, Johann D D Pitout^4,5,6

¹Alberta Precision Laboratories, Calgary, AB, Canada.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

|September 26, 2025

概括

在全球范围内,产生碳酶的Serratia物种表现出多样化的物种和克隆,其中KPC,VIM和NDM碳酶是最常见的. 全基因组测序揭示了克隆和多克隆传播模式.

科学领域:

微生物学微生物学
基因组学就是基因组学.
流行病学流行病学

背景情况:

关于产生卡巴酶的Serratia物种的全球分子流行病学数据有限.
碳酶产生肠道细菌 (CPE) 是一个重要的公共卫生问题.

研究的目的:

为了描述全球分子流行病学,卡巴酶产生Serratia spp.
为了确定流行的卡巴基,物种,克隆和传播模式.

主要方法:

全基因组测序 (WGS) 的56个卡巴酶产生Serratia spp. 孤立的. 孤立的.
分析2015-2017年间全球监测计划中分离的样本.

主要成果:

KPC (54%),VIM (16%) 和NDM (14%) 是最常见的碳化合物.
塞拉蒂亚·萨鲁曼尼 (32%),塞拉蒂亚·内维 (23%) 和塞拉蒂亚·马塞森斯 (20%) 是主要的物种.
观察到克隆和多克隆传播,根据物种,克隆和地理位置而有所不同. 在欧洲和台湾流通的I类整体.

结论:

产生碳酶的Serratia spp. 的植物. 在物种,克隆和碳烯酶类型方面表现出显著的全球多样性.
WGS提供了关于CPE全球流行病学的详细见解.
需要对Serratia物种进行分类学澄清.

关键词:

产生碳酶的Serratia spp. 的植物.全球基因组流行病学

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