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Updated: Jan 6, 2026

Single-cell Screening Method for the Selection and Recovery of Antibodies with Desired Specificities from Enriched Human Memory B Cell Populations
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Single-cell Screening Method for the Selection and Recovery of Antibodies with Desired Specificities from Enriched Human Memory B Cell Populations

Published on: August 22, 2019

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细胞选择性向化马体 (SelecTACB) 对B细胞的膜蛋白降解

Zhenlin Yang1,2,3, Jianfei Jiang1,2,3, Yuhui Cao1,3

  • 1Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University Beijing 100871, China.

Journal of the American Chemical Society
|September 26, 2025
PubMed
概括

研究人员开发了SelecTACB, 这是一种针对蛋白质降解的新奇工具. 这项技术选择性地降解B细胞上的膜蛋白,为免疫细胞治疗提供了一种新策略.

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High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

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Bacterial Inner-membrane Display for Screening a Library of Antibody Fragments12:28

Bacterial Inner-membrane Display for Screening a Library of Antibody Fragments

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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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