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突变RIT1与YAP合作,驱动一个类似于EMT的肺癌状态

Mary C Rominger1, Siobhan O'Brien1, Saksham Gupta1

  • 1Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.

Cell reports
|September 26, 2025
PubMed
概括

研究人员开发了一种针对RIT1突变肺癌的新老鼠模型. 该模型显示,RIT1驱动了侵袭性癌症,为开发向治疗提供了一个平台.

关键词:
AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1CP: 癌症 癌症 癌症在EMT中,EMT是EMT.这就是GEMM.这是一个GTPase.河马河马是什么意思 海马河马是什么意思拉斯拉斯拉斯拉斯拉斯拉斯拉斯拉斯拉斯在RIT1中,它是RIT1的.哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈表皮细胞到介质细胞的过渡.肺癌是一种肺癌.

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