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在非综合性口唇裂患者和健康对照者之间对喉气道尺寸的比较:系统性审查和元分析
Farzaneh Ahrari1, Neda Eslami2, Erfan Bardideh3
1Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
概括
与健康个体相比,非综合性口唇裂 (CLP) 患者的喉气道尺寸显著减少,特别是在耳鼻和耳鼻. 裂口类型,年龄和性别并没有显著影响这些气道缩小.
科学领域:
- 头骨面部解剖学 头骨面部解剖学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 医学成像分析分析 医学成像分析
背景情况:
- 唇裂 (CLP) 是一种常见的先天性疾病,影响面部结构.
- 喉气道尺寸可能会受到面异常的影响.
- 了解这些变化对于管理CLP患者至关重要.
研究的目的:
- 系统地评估和比较非综合征性CLP患者与健康对照者的喉气道尺寸.
- 为了确定喉中受CLP影响最严重的特定区域.
- 评估裂类型,年龄和性别对喉气道尺寸的影响.
主要方法:
- 进行了39项临床研究的系统审查和元分析.
- 包括非综合征性唇裂 (CLP) 患者和健康的对照组.
- 利用随机效应逆方差元分析来合成关于喉气道体积和最小横截面积的数据.
主要成果:
- 与对照人群相比,非综合性CLP患者的喉气道总体,耳鼻喉和耳鼻喉体积显著减少.
- 没有发现鼻或鼻下垂体体积的显著差异.
- 喉的最小横截面积在CLP患者中明显较小.
结论:
- 在非综合征性CLP患者中,喉气道尺寸,特别是耳鼻和耳鼻显著减少.
- 裂口类型,患者年龄和性别不会显著改变喉气道尺寸缩小的程度.
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