儿科长期COVID综合征对视觉感知和神经心理症状的长期影响
Tzu-Yu Chen1, Yen-Ju Chu2, Chia-Jui Hsu3
1Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei, Taiwan.
Pediatric neurology
|September 26, 2025
概括
儿科长期COVID患者表现出神经精神症状和视觉感知问题,与大脑灰质体积变化有关. 症状严重程度在急性阶段可以预测长期的大脑变化.
科学领域:
- 儿科神经学 儿科神经学
- 神经成像是一种神经成像.
- 传染性疾病的后果 传染性疾病的后果
背景情况:
- 长期COVID (SARS-CoV-2感染的急性后续) 呈现出各种持续症状.
- 关于长期COVID对儿童和青少年的影响的数据有限.
- 这项研究调查了儿童长期COVID的视觉感知,神经精神症状和大脑体积.
研究的目的:
- 在儿科长期COVID中探索视觉感知和神经精神症状.
- 检查这些症状与大脑体积差异之间的关联.
- 评估症状严重程度和神经成像发现之间的关系.
主要方法:
- 招募了60名儿科参与者 (6-18岁) 在COVID-19感染后5-8个月.
- 使用加权评分系统评估症状,并根据严重程度划分参与者.
- 进行磁共振成像 (MRI) 并进行视觉感知技能测试-第四版 (TVPS-4).
主要成果:
- 常见的症状包括头痛,头,注意力和记忆力缺陷.
- 严重症状组显示灰质体积增加,特别是在皮下和部区域.
- 与对照组相比,在视觉症状的参与者中发现了显著的视觉感知差异 (整体和顺序记忆).
结论:
- 儿科长期COVID与神经精神症状,视觉知觉受损和灰色物质体积变化有关.
- 急性期神经精神病症状的严重程度可能预测慢性期大脑体积变化.
- 需要进一步的纵向研究来证实这些发现.
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