在营养不良住院患者的干预后,对临床结果的评估
Yolanda Garcia1, Nere Larrea2, Josune Martin2
1Osakidetza Basque Health Service, Galdakao-Usansolo University Hospital, Endocrinology Service, Galdakao, Spain; BioBizkaia Health Research Institute, Barakaldo, Spain.
Clinical nutrition (Edinburgh, Scotland)
|September 26, 2025
概括
对患有疾病相关营养不良 (DRM) 的住院患者进行营养干预并没有降低30天死亡率或90天再入院率. 然而,干预措施在继续下放后显示出对90天死亡率的好处.
科学领域:
- 临床营养学 临床营养学
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
背景情况:
- 与疾病相关的营养不良 (DRM) 与增加的死亡率,功能减弱和长时间住院有关.
- 评估营养干预措施对于改善DRM住院患者的治疗结果至关重要.
研究的目的:
- 评估在被诊断为患有疾病相关营养不良 (DRM) 的住院患者的营养干预措施的有效性.
主要方法:
- 一项实用性有效性研究涉及3所大学医院的1051名患者,他们患有各种癌症,胰腺炎或炎症性肠道疾病 (IBD).
- 患者被分为三个组:没有DRM,中度至重度DRM与营养干预,中度至重度DRM与标准护理.
- 诊断DRM使用MUST和GLIM标准;生存,物流回归和多层模型被用于分析.
主要成果:
- 在DRM和非DRM组之间没有观察到30天死亡率或90天再入院的显著差异.
- 没有干预的DRM患者有更高的90天死亡风险,但这在干预组中没有观察到.
- 两个DRM组的住院时间都更长,从入院到出院的时间,感染并发症或营养参数的变化没有差异.
结论:
- 营养干预证明对离院后死亡率有好处.
- 建议在出院后持续提供营养支持,以最大限度地提高患者的益处.
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