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Updated: Jan 16, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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改造的细菌外膜囊泡增强了瘤免疫疗法,通过重塑瘤层和针对性地输送CD73siRNA

Lili Cheng1, Dan Peng1, Zhuoyin Liu1

  • 1School of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong, 518107, PR China.

Biomaterials
|September 26, 2025
PubMed
概括

工程化细菌外膜囊泡 (OMVs) 降解瘤细胞外基质,并提供siRNA来抑制CD73,增强免疫疗法并减少瘤生长和转移.

关键词:
细菌外膜囊泡是一种细菌外膜囊泡.在CD73-adenosine轴上细胞外矩阵是细胞外矩阵.瘤免疫疗法免疫疗法siRNA的传递方式

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