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Updated: Jan 16, 2026

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NFS1,与FXN一起,在扩散大B细胞淋巴瘤中保护细胞免受铁亡和DNA损伤

Xue Shi1, Yun Zhao2, Hong-Yu Gao1

  • 1Department of Hematology, Shengjing Hospital of China Medical University, Shenyang, China.

Redox biology
|September 26, 2025
PubMed
概括

铁硫生物发生中的关键蛋白质NFS1和FXN保护扩散型大B细胞淋巴瘤 (DLBCL) 细胞免受铁亡和DNA损伤. 抑制这些蛋白质抑制DLBCL瘤生长,提供潜在的治疗点.

关键词:
DLBCL DLBCL 是一个字母.造成的DNA损伤是DNA损伤.在 FXN 和 FXN 之间.铁性化 (ferroptosis) 是一种美国国家金融服务体系 (NFS1)

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