帕金森病患者脊柱形手术后的结果:一种倾向匹配分析
Austin H Carroll1, James Fookes2, Alejandro Quinonez2
1Medstar Georgetown University Hospital, Department of Orthopaedic Surgery, Washington, D.C., USA.
概括
患有帕金森病 (PD) 的患者接受脊柱形手术,面临更高的医学并发症和手术修订风险. 对于这个高风险群体,首先建议进行非手术治疗.
科学领域:
- 整形外科 整形外科 整形外科
- 神经外科 神经外科
- 老年病的医生 老年病的医生
背景情况:
- 成年脊柱形手术具有很高的并发症率 (大约. 40%). 在这个问题上.
- 帕金森病 (PD) 患者因脊柱硬和勃拉迪基尼西亚而增加脊柱形的易感性.
- 在PD患者的多层次脊柱形手术结果上存在有限的研究.
研究的目的:
- 与匹配的对照组相比,研究帕金森病 (PD) 患者多层次后脊髓融合的结果.
- 为了评估医疗并发症,手术部位感染 (SSI) 和术后修复率.
主要方法:
- 来自PearlDiver数据库的2776名患者的回顾性分析,这些患者因脊柱形而经历了多级后脊柱融合.
- 1388名患有PD的患者的倾向与基于年龄,查尔森并发症指数 (CCI) 和埃利克沙瑟并发症指数 (ECI) 的对照组进行了1:1的匹配.
- 评估结果包括90天的医疗并发症,90天的SSI率和2年的外科修复率.
主要成果:
- 患有PD的患者在2年后显示出明显更高的外科修复率.
- 患有PD的患者在术后90天经历了医学并发症的风险增加.
- 在PD和对照组之间没有观察到90天手术部位感染 (SSI) 率的显著差异.
结论:
- 与匹配的对照组相比,PD患者脊柱形多层次后脊柱融合与增加的医疗并发症和外科修复风险有关.
- 在考虑对患有脊椎形的PD患者进行手术干预之前,消耗非手术管理选项至关重要.
- 进一步的研究是必要的,以优化这种高风险人群的手术结果.
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