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Updated: Jan 16, 2026

Deacetylation Assays to Unravel the Interplay between Sirtuins SIRT2 and Specific Protein-substrates
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Published on: February 27, 2016

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脱乙酶SIRT1调节抗病毒先天免疫力和自身免疫性疾病

Shuang-Shuang Yu1, Hengxiang Yu1, Shijin Geng1

  • 1Department of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Medicine Innovation Center for Fundamental Research on Major Immunology-related Diseases, Peking University, Beijing 100191, China.

International journal of biological macromolecules
|September 26, 2025
PubMed
概括

赛尔图因1 (SIRT1) 通过去乙IRF3/IRF7,抑制干扰素的产生来负面调节抗病毒反应. 抑制SIRT1增强抗病毒免疫力,并显示病毒感染和自身免疫性疾病的治疗潜力.

关键词:
脱乙化 脱乙化 脱乙化在 IRF3 中,IRF3 是 IRF3 的一个类型.在IRF7中,IRF7是什么?这是天生的免疫力.酸化是指酸化的方法.一个SIRT1系统.

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