澳大利亚零售蔬菜和家庭表面上的Clostridioides (Clostridium) difficile的流行率和分子类型
Deirdre A Collins1, Su Chen Lim1, Jessica Chisholm2
1School of Medical & Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia; School of Biomedical Sciences, The University of Western Australia, Crawley, Western Australia, Australia.
Anaerobe
|September 26, 2025
概括
艰难菌感染 (CDI) 在社区中越来越常见. 这项研究在零售蔬菜和家庭中发现了C. difficile,这表明这种感染有可能在家庭中传播.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 社区发病的Clostridioides difficile感染 (CDI) 现在占澳大利亚80%以上的病例.
- 在社区来源中,C. difficile污染很普遍,包括零售根蔬菜.
- 在储存和处理受污染的蔬菜时,家庭表面可能受到污染.
研究的目的:
- 为了确定C. difficile在零售根蔬菜上的流行率.
- 为了确定这些蔬菜上发现的C. difficile的分子类型.
- 评估与蔬菜处理相关的家庭表面上C. difficile的存在.
主要方法:
- 在12个月内采样零售土豆 (n=255) 和洋 (n=305).
- 从昆士兰州和西澳大利亚州的229个家庭收集了环境抽样.
- 样品经过丰富培养,随后进行PCR核型定型和毒素基因检测.
主要成果:
- 在5.6%的家庭样本中检测到C. difficile,35.3%的土豆样本和20.3%的洋样本.
- 15.7%的家庭至少有一个阳性样本 (蔬菜或环境).
- 主要的C. difficile核型因地区而异,在华盛顿西部有056,286,101和125个常见的菌株,在QLD有101,QX 098,014/020和QX 601个.
结论:
- 在零售蔬菜和家庭中发现有毒的C. difficile菌株.
- 这突出了在家庭环境中获得CDI的潜在途径.
- 高风险人群可以从安全处理和清洁潜在C. difficile来源的教育中受益.
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