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Updated: Jan 16, 2026

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
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Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer

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在结肠直肠腺瘤 - 癌症的进展中,作为预后标志物,瘤和相邻的粘膜之间的PCNA表达差异是结肠直肠腺瘤 - 癌症的进展

Revekka Harisi1,2,3, Balazs Jaray4, Attila Zsirka5

  • 11 Institute of Pathology and Experimental Cancer Research, Faculty of Medicine, Semmelweis University, Budapest, Hungary; harisi.revekka@semmelweis.hu.

Anticancer research
|September 26, 2025
PubMed
概括

增殖细胞核抗原表达差异 (PCNA-ED) 是结直肠瘤进展的重要指标. 较高的PCNA-ED与恶性瘤增加,复发和较差的存活率相关,有助于预后.

关键词:
腺瘤 - 癌瘤序列这是一个PCNA,PCNA,PCNA.腺瘤腺瘤是一种结肠直肠癌是什么意思聚合物 (polyp) 是一种多重体.

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Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
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