结肠癌的生存影响和社会人口统计相关因子 手术拒绝结肠癌手术
Paola Berrios Jimenez1, Angel Aguayo Merly2, Ramin Shekouhi3
1School of Medicine, University of Puerto Rico, San Juan, PR, U.S.A.; paola.berrios2@upr.edu.
Anticancer research
|September 26, 2025
概括
结肠癌患者的手术拒绝与年龄较大,女性性别,黑人种族和非私人保险有关. 拒绝手术的患者的生存率明显较低,突出了癌症治疗结果的差异.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 健康差异 在健康上的差异
背景情况:
- 结肠癌的早期诊断往往导致治疗性手术治疗.
- 了解影响手术拒绝的因素对于改善患者的治疗结果至关重要.
- 这项研究调查了与结肠癌手术拒绝相关的社会人口统计特征和生存率.
研究的目的:
- 评估与结肠癌手术拒绝相关的社会人口因素.
- 为了比较接受手术和拒绝接受手术的患者之间的生存结果.
- 为了识别结肠癌手术治疗的差异.
主要方法:
- 从2004年至2019年使用国家癌症数据库 (NCDB) 进行回顾性队列研究.
- 对1,048,575名结肠癌患者的分析,检查了人口统计,瘤特征和社会经济因素.
- 卡普兰-梅尔分析和Cox相称危险回归用于生存结果.
主要成果:
- 在1.0%的患者中观察到拒绝手术;老年女性,黑人患者和非私人保险患者的拒绝率更高.
- 与整体队列 (平均68.1岁) 相比,拒绝手术的患者年龄较大 (平均80.8岁).
- 拒绝手术的患者 (55%) 的五年生存率明显低于接受手术的患者 (66%).
结论:
- 高龄,黑人种族,女性性别,低收入和非私人保险与更高的结肠癌手术拒绝率有关.
- 手术干预为结肠癌患者提供了显著的生存益处.
- 需要有针对性的干预措施来解决治疗差异,并加强患者对手术结果的教育.
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