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兰暴露及其对Ruditapes philippinarum的代谢效应

Fabrizio Mastrorocco1, Marco Vito Guglielmi2, Luca De Martino1

  • 1Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), National Research Council (CNR), Via Amendola n. 122/O, Bari, 70126, Italy.

Scientific reports
|September 26, 2025
PubMed
概括

海洋生态系统中的兰 (La) 污染损害了马尼拉,Ruditapes philippinarum. 暴露导致组织损伤和代谢中断,突出显示了稀土元素 (REEs) 污染的生态风险.

关键词:
生物标志物 生物标志物克拉姆 (Clam Clam) 是一种类型的鱼.兰他是一种.地中海水产养殖 地中海水产养殖它的代谢物是代谢物.

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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...