根据出生体重的长期结果在满期怀孕后:全国一项队列研究
Kyong-No Lee1, Heechul Jeong2, Geum Joon Cho3
1Department of Obstetrics and Gynecology, Chungnam National University College of Medicine, Chungnam National University Hospital, Daejeon, Republic of Korea.
Scientific reports
|September 26, 2025
概括
在满期婴儿中,极低或高的出生体重 (BW) 与神经和神经发育迟缓的风险增加有关. 低BW和高BW都对新生儿造成了重大健康问题.
科学领域:
- 新生儿健康 新生儿健康
- 发育儿科 发育儿科
- 公共卫生 公共卫生
背景情况:
- 出生体重 (BW) 是新生儿健康和发育的关键指标.
- 偏离典型的BW范围可能会影响长期的健康结果.
- 了解BW-结果关系对于早期干预至关重要.
研究的目的:
- 为了研究出生体重 (BW) 与长期神经或神经发育结果之间的联系,在满期新生儿中.
- 确定与风险增加相关的特定BW百分位数.
- 分析这种关系的分布.
主要方法:
- 使用韩国国家医疗保险索赔数据库进行的回顾性观察队列研究.
- 包括514,166个孕期满期的母婴对.
- 基于诊断和随访对神经/神经发育结果的评估.
主要成果:
- 在新生儿BW和神经/神经发育迟缓之间观察到J形分布.
- 婴儿在BW第三百分位以下的婴儿有1.24调整后的危险比率延迟 (vs对照).
- 在第97百分比以上的婴儿中,BW的延迟 (与对照) 的调整危险比率为1.09.
结论:
- 极低出生体重和高出生体重都与早产婴儿神经和神经发育迟缓的风险增加有关.
- 这些发现强调了监测BW极端的重要性,以发现潜在的发展问题.
- 这项研究强调了BW和长期婴儿神经发育轨迹之间的复杂关系.
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