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Updated: Jan 16, 2026

Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations
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预测非编码变异对基因表达的调控影响,通过跨组织和单细胞格局的表观基因组合来预测

Zhe Liu1, Yihang Bao1, An Gu1

  • 1Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.

Nature computational science
|September 26, 2025
PubMed
概括

新的人工智能模型EMO通过整合DNA序列和染色质数据来预测遗传突变如何影响基因表达. 这种工具可以在各种组织和细胞类型中进行个性化,特定于疾病的预测.

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