开发一种开源的3D成像方法,用于基于中枢关节骨骨化进行法医年龄估计:评估体和元体的面积和体积比率
Jonathan Kurz1, Tobias Krähling2, Ronald Schulz1
1Institute of Legal Medicine, University of Münster and University Hospital Münster, Röntgenstraße 23, 48149, Münster, Germany.
International journal of legal medicine
|September 27, 2025
概括
使用中枢关节骨3DCT扫描的法医年龄估计提供了一种可重复的方法. 这种定量方法克服了传统视觉分期的局限性,用于在缺少文档时准确评估年龄.
科学领域:
- 法医人类学 法医人类学
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 法医年龄估计对于缺乏文件的法律和社会背景至关重要.
- 由于解剖学变异,中枢关节突突 (MCE) 骨化的传统视觉分期容易出现错误.
- 高分辨率计算机断层扫描 (CT) 提供了定量形态测量分析的潜力.
研究的目的:
- 开发一个开源的工作流程,用于使用中枢关节的3DCT细分测量年龄估计.
- 为了能够对MCE进行定量形态测量评估,以改善法医年龄估计.
- 为年龄评估提供透明和合作验证的方法.
主要方法:
- 开发了一个基于Hua等的开源工作流. (2014) 用于3DCT细分和形态分析.
- 使用伪名的临床CT扫描存档在XNAT中,在3D Slicer中生成3D模型.
- 通过专家指导的细分和对齐,从形和形相中提取了定量参数 (面积,体积,比率).
主要成果:
- 成功开发了一种半自动的3D CT细分工作流程,用于中枢关节骨形态测量.
- 提取的无维度指标 (面积/体积比) 用于定量年龄估计.
- 通过3D成像证明了通过3D成像对中间关节骨的形态测量评估的潜力.
结论:
- 使用3DCT成像对中间关节骨的形态测量评估是法医年龄估计的一个有前途的方法.
- 开源工作流促进了透明度,并促进了协作验证.
- 未来的工作应该集中在验证指标标记和自动化复杂案例的工作流.
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