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肝细胞中的一个非亡性caspase-8-meteorin通路促进MASH纤维化

Xiaobo Wang1,2, Mary P Moore3, Hongxue Shi3

  • 1Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA. xw2279@columbia.edu.

Nature metabolism
|September 27, 2025
PubMed
概括

代谢功能障碍相关的脂肪肝炎 (MASH) 通过肝细胞卡斯帕-8引起肝纤维化,独立于亡. 这一途径涉及石,一种新的肝星细胞激活剂,提供新的治疗点.

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