Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Mechanism of Lamellipodia Formation01:31

Mechanism of Lamellipodia Formation

3.6K
Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...
3.6K
Cells of the Epidermis01:24

Cells of the Epidermis

6.7K
The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
The cells in all these layers except the stratum basale are called keratinocytes, a type of cell that manufactures and stores the protein keratin. The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from...
6.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Microstructured chitosan mesh scaffold for efficient production of cell-cultured meat.

Scientific reports·2026
Same author

Loss of p53 Provokes NF-κB-Dependent Disruption of Nucleolar Cap and Nucleoplasmic Redistribution of Fibrillarin During Nucleolar Stress.

Biomolecules·2026
Same author

Discovery of non-opioid peptides that selectively relieve mechanical pain in rodents through inhibition of TRPV4 channels.

Acta pharmacologica Sinica·2026
Same author

Celastrol and Cblin peptide activation of IGF-1 signaling prevents microgravity-induced atrophy in rat L6 myotubes.

American journal of physiology. Cell physiology·2025
Same author

Mechanosensitive channels are versatile exporters in microbial cell factories.

The Journal of general and applied microbiology·2025
Same author

A synthetic peptide, derived from neurotoxin GsMTx4, acts as a non-opioid analgesic to alleviate mechanical and neuropathic pain through the TRPV4 channel.

Acta pharmaceutica Sinica. B·2025

相关实验视频

Updated: Jan 16, 2026

Generation of Multicue Cellular Microenvironments by UV-Photopatterning of Three-Dimensional Cell Culture Substrates
09:30

Generation of Multicue Cellular Microenvironments by UV-Photopatterning of Three-Dimensional Cell Culture Substrates

Published on: June 2, 2022

2.9K

角质细胞在步骤模式基板上形成光滑板的能力.

Nozomu Kitamura1, Shoichi Makara2, Masami Kojima1

  • 1Department of Life Science and Biotechnology, Kanazawa Institute of Technology, Hakusan 924-0838, Ishikawa, Japan.

Bioengineering (Basel, Switzerland)
|September 27, 2025
PubMed
概括
此摘要是机器生成的。

皮肤角质细胞在不均的表面上自组织成光滑的薄片. 这一过程对皮肤屏障功能至关重要,涉及细胞密度的变化,并需要细胞粘附和增殖,以获得适当的表皮结构.

关键词:
粘附于连接口的结口.细胞的增殖细胞的增殖.皮肤表皮的表皮.质细胞 (keratinocyte) 是一种细胞.微型制造是指微型制造.组织形态发生的组织形态发生.

更多相关视频

Preparation of Tunable Extracellular Matrix Microenvironments to Evaluate Schwann Cell Phenotype Specification
07:50

Preparation of Tunable Extracellular Matrix Microenvironments to Evaluate Schwann Cell Phenotype Specification

Published on: June 2, 2020

5.7K
Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates
07:19

Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates

Published on: March 7, 2014

13.8K

相关实验视频

Last Updated: Jan 16, 2026

Generation of Multicue Cellular Microenvironments by UV-Photopatterning of Three-Dimensional Cell Culture Substrates
09:30

Generation of Multicue Cellular Microenvironments by UV-Photopatterning of Three-Dimensional Cell Culture Substrates

Published on: June 2, 2022

2.9K
Preparation of Tunable Extracellular Matrix Microenvironments to Evaluate Schwann Cell Phenotype Specification
07:50

Preparation of Tunable Extracellular Matrix Microenvironments to Evaluate Schwann Cell Phenotype Specification

Published on: June 2, 2020

5.7K
Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates
07:19

Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates

Published on: March 7, 2014

13.8K

科学领域:

  • 细胞生物学 细胞生物学
  • 组织工程是组织工程.
  • 皮肤病学 皮肤病学

背景情况:

  • 外皮结构对于皮肤屏障功能至关重要.
  • 皮肤表面保持平滑的表面,尽管底层的地形变化.
  • 表面皮肤适应基底地形的机制尚未完全理解.

研究的目的:

  • 为了研究质细胞如何适应其架构与有图案的基板.
  • 阐明形成光滑表皮表面的细胞机制.

主要方法:

  • 使用了带有步骤特征的微型图案基板.
  • 在这些基质上观察了角质细胞的行为和叶片的形成.
  • 分析了细胞密度,细胞间粘附和增殖.

主要成果:

  • 角质细胞在有图案的基板上自主形成了光滑的细胞板.
  • 在步骤边缘观察到质细胞密度增加,从而产生对数斜率.
  • 附着物结合介导的粘附和细胞增殖对于光滑的板块形成至关重要.

结论:

  • 角质细胞群形态发生证明了对基底地形的强度.
  • 研究结果为皮肤组织工程的表皮结构维护提供了洞察力.
  • 这项研究阐明了角质细胞如何集体塑造皮肤表面.