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突变分析揭示了METTL16域和残留物的功能作用

Kurtis Breger1, Ian P Schowe1, Noah A Springer1

  • 1Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.

Biology
|September 27, 2025
PubMed
概括

人类甲基转移酶样蛋白16 (METTL16) 对于RNA甲基化至关重要. 这项研究揭示了U6 snRNA和S-adenosylmethionine (SAM) 结合和甲基化活性至关重要的特定残留物和区域.

关键词:
在METTL16中,METTL16是METTL16中的一个.这是一种N6-甲基氨酸.在U6 snRNA中.甲基转移酶的使用方法

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