结合心率变异性和加速性胸膜扫描与系统性并发性疾病负担在患有玻璃眼的患者中
Yuto Yoshida1, Hinako Takei1, Misaki Ukisu1
1Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo 693-8501, Japan.
Biomedicines
|September 27, 2025
概括
青光眼患者的系统性并发症负担较高与自主神经系统 (ANS) 调节较差以及血管度增加有关. 这项研究探讨了心率变化 (HRV) 和加速度囊造影 (APG) 之间的联系,以及玻璃眼病的并发症指数.
科学领域:
- 眼科医生 眼科 眼科
- 心脏病学 心脏病学
- 神经学 神经学
背景情况:
- 玻璃眼与自主神经系统 (ANS) 和血管因素有关.
- 系统性并发症负担与青光眼患者的ANS/血液动力学功能之间的关系尚不清楚.
研究的目的:
- 为了研究心率变化 (HRV) 和加速囊造影 (APG) 参数与老年调整的查尔森并发症指数 (ACCI) 之间的关联.
主要方法:
- 分析了260名玻璃眼患者 (186名初级开角玻璃眼患者,74名脱皮玻璃眼患者).
- HRV和APG的参数是使用血压仪测量.
- 使用斯皮尔曼等级相关性和多变量回归来评估与ACCI的关联,调整为混因素.
主要成果:
- ACCI显示了与几个HRV和APG参数的显著反相关性.
- 多变量分析显示,ACCI与RMSSD正相关,与LnLF和LnLF/LnHF (HRV) 有负相关.
- ACCI与c峰值 (APG) 和B型血管性显著相关.
结论:
- 青光眼患者的系统性并发症负担增加可能与ANS调节受损相关.
- 较大的并发症负担也可能与这种人群的血管硬性增加有关.
相关概念视频
Glaucoma: Overview
1.2K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.2K
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
363
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
363
Open Angle Glaucoma: Treatment
963
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
963
Hypertension III: Clinical Manifestations and Diagnostic Studies
471
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
471
Measurement of Blood Pressure
2.7K
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
2.7K


