洛卡赛林和贝塔希斯联合治疗改善了饮食诱导肥胖症的小鼠模型中的认知功能障碍和多巴胺基神经元活动

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Published on: July 31, 2021

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Ike de la Peña1, Johnny Figueroa2, Wei-Xing Shi1,3

  • 1Department of Pharmaceutical and Administrative Sciences, Loma Linda University School of Pharmacy, Loma Linda, CA 92350, USA.

Brain sciences
|September 27, 2025
PubMed
概括

与洛卡赛林和贝塔希斯联合治疗通过增强多巴胺基神经元活动,在不影响体重的情况下,在老鼠中逆转了与肥胖相关的认知缺陷. 这为肥胖引起的记忆障碍提供了潜在的治疗方法.

关键词:
贝塔希斯类药物 (betahistine) 是一种认知 认知 认知结合治疗治疗的组合治疗.洛卡塞林 (Lorcaserin) 是一种肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖前额叶皮层前额叶皮层.

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