在老年西班牙裔人中,糖尿病,认知功能和死亡风险
Jagdish Khubchandani1, Elizabeth England-Kennedy1, Srikanta Banerjee2
1College of Health, Education, and Social Transformation, New Mexico State University, MSC 3AC, P.O. Box 30001, Las Cruces, NM 88003, USA.
Brain sciences
|September 27, 2025
概括
糖尿病和认知障碍一起显著增加老年西班牙裔成年人的死亡风险. 这种双重负担几乎使死亡风险增加了一倍,突显了针对性健康战略的必要性.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 糖尿病是全球主要的死亡原因,与衰老和认知能力下降有关.
- 诸如血管损伤和胰岛素抵抗等共享机制连接了糖尿病和认知障碍.
- 对老年西班牙裔成年人死亡率的综合影响尚未得到充分研究.
研究的目的:
- 调查与老年西班牙裔成年人同时存在的糖尿病和低认知能力相关的死亡风险.
- 在面临双重健康负担的边缘化人口中解决健康差异.
主要方法:
- 利用了来自NHANES (1999-2002) 的636名西班牙裔成年人 (≥60岁) 的数据,并将死亡率跟踪到2019年.
- 采用Cox的比例危险模型来评估所有原因的死亡风险.
- 调整以社会人口统计和与健康相关的共同变量.
主要成果:
- 23.3%的人患有糖尿病,54.9%的人认知能力低下.
- 糖尿病和低认知能力的组合显示,所有原因死亡风险增加了2.36倍 (HR=2.36;95% CI:1.70-3.28).
- 无论是糖尿病还是认知障碍本身都没有显著增加死亡风险.
结论:
- 同时存在的糖尿病和认知障碍在老年西班牙裔成年人中显著增加了死亡风险.
- 调查结果强调了对老龄化少数群体的文化定制,跨学科方法的需要.
- 解决糖尿病和认知衰退的双重负担对于这个人口群体至关重要.
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