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Working Memory01:24

Working Memory

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Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
803
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

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Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
776
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

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Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
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Information Processing Approach01:30

Information Processing Approach

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The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
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相关实验视频

Updated: Jan 16, 2026

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
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在ADHD中提高工作记忆:自适应双N-Back训练提高WAIS-IV性能,但产生混合Corsi结果.

Alessandra Lintas1,2, Michel Bader3, Alessandro E P Villa1

  • 1NeuroHeuristic Research Group, University of Lausanne, Quartier UNIL-Chamberonne, 1015 Lausanne, Switzerland.

Brain sciences
|September 27, 2025
PubMed
概括

使用双N背任务进行工作记忆训练,改善了ADHD年轻成年人的认知表现. 适应性训练对口头工作记忆有更大的益处,对视觉空间技能的转移有限.

关键词:
注意缺陷/多动障碍 (ADHD) 是一种注意缺陷/多动障碍.认知增强 认知增强 认知增强双 N-背任务任务.执行职能 执行职能是指执行职能.工作记忆训练工作记忆训练

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科学领域:

  • 认知神经科学 认知神经科学
  • 神经心理学 神经心理学
  • 精神病学是一个精神病学.

背景情况:

  • 注意缺陷/多动障碍 (ADHD) 与工作记忆缺陷有关.
  • 工作记忆训练 (WMT) 是一种潜在的认知增强干预策略.
  • 双N-back (DNB) 任务是一个苛刻的WMT协议,针对工作内存容量.

研究的目的:

  • 评估DNB培训对ADHD年轻成年人认知表现的有效性.
  • 为了比较固定与自适应DNB培训协议的效果.
  • 评估对未经训练的认知任务的转移效应.

主要方法:

  • 106名参与者 (ADHD和对照组) 在一个月内每天至少进行18次DNB会话.
  • 随机分配到固定的双一背 (FD1B) 或自适应的DNB条件.
  • 使用WAIS-IV工作记忆指数和Corsi Block-Tapping任务干预前后进行认知评估.

主要成果:

  • 所有组都表现出更好的DNB表现;适应性训练带来了显著更大的收益.
  • WAIS-IV工作记忆指数得分,特别是数字跨度向后,在适应性训练中得到了更大的改善.
  • 在Corsi的性能中观察到的收益有限,与FD1B训练有着令人惊的关联.

结论:

  • 双N背训练有效地提高了ADHD的年轻成年人的口头工作记忆.
  • 适应性训练协议似乎更有利于改善工作记忆.
  • 对视觉空间领域的转移效应是有限的,可能不会对不同的人群进行概括.