在非糖尿病人群中,BAN评分和明显的早期心脏代谢风险特征:横截面分析
Yazeed Alshuweishi1, Noha A Alshuwayer2, Lama Izziddeen3
1Chair of Medical and Molecular Genetics Research, Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia.
体重指数-白蛋白-中性粒细胞-淋巴细胞 (BAN) 评分与早期心脏代谢风险有关,如高血压和非糖尿病成年人的血糖变化. 这一分数可能有助于识别患心血管和代谢疾病风险的个体.
科学领域:
- 心脏病学 心脏病学
- 代谢健康 代谢健康
- 生物标志物 生物标志物
背景情况:
- 体重指数-白蛋白-中性粒细胞-淋巴细胞 (BAN) 评分结合了脂肪,营养状况和炎症.
- 它在检测非糖尿病人早期心脏代谢变化的实用性尚未得到充分证实.
研究的目的:
- 调查BAN得分与血管,血糖和脂质标记物之间的关联.
- 评估BAN得分作为心脏代谢风险早期指标的潜力.
主要方法:
- 对162名非糖尿病成年人的回顾性横截面研究.
- 分析包括斯皮尔曼相关性,ROC分析和调整后回归模型.
- 评估了血管 (SBP,PP),血糖 (HbA1c) 和脂质参数.
主要成果:
- 较高的BAN分数与缩血压 (SBP),脉冲压 (PP) 和HbA1c的增加相关.
- 调整后的模型显示,BAN得分的增加与更高的SBP,PP和HbA1c有关.
- BAN评分显示了对高血压和HbA1c升高的中度区分能力.
结论:
- 该BAN得分与早期心脏代谢风险因素有关,包括SBP升高,PP扩大和血糖变化.
- 需要进一步的研究来阐明BAN得分的潜在机制及其预防策略的潜力.
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