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Updated: May 13, 2026

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转录组分析揭示了卵巢癌中CD4+ T细胞和Treg细胞的分化

Baoyi Shao1, Bo Sun1, Zhongdang Xiao1

  • 1State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.

Biomolecules
|September 27, 2025
PubMed
概括

调节性T细胞 (Tregs) 主导卵巢癌瘤,影响患者的存活率. 这项研究揭示了Tregs.

关键词:
在CD4+ T细胞中,有CD4+ T细胞.在Treg细胞中.卵巢癌是发生在卵巢的癌症.转录组 (transcriptome) 是一个转录组.瘤免疫微环境是一个微环境.

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T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...