在现代成像时代对光盘的系统审查:结构功能相关性,诊断性能和NAION同时发生
Alina Dumitriu1,2, Bogdan Dumitriu1, Flavius George Socol1
1Doctoral School, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Diagnostics (Basel, Switzerland)
|September 27, 2025
概括
光盘干燥 (ODD) 导致结构变化和视力丧失,模仿皮质瘤. 多模式成像显示了ODD.
科学领域:
- 眼科医生 眼科 眼科
- 神经眼科神经眼科
- 医疗成像医学成像
背景情况:
- 光盘干 (ODD) 常常被误认为是乳头,这种情况表明内压力增加.
- ODD与结构拥挤,微血管变化和潜在的视野缺陷有关.
- 了解ODD的影响对于准确的诊断和患者管理至关重要.
研究的目的:
- 综合当前关于ODD结构和微血管差异的证据.
- 评估ODD患者视野损失的功能状态和进展情况.
- 评估各种成像模式的诊断性能和ODD与非动脉炎前面缺血性视神经病变 (NAION) 的同时发生情况.
主要方法:
- 在PubMed,Embase和Web of Science进行了系统的文献搜索,遵守PRISMA指南.
- 符合条件的研究包括横截面,队列和诊断准确性研究,具有 OCT,OCTA,视野和 NAION 流行率等定量结果.
- 两个独立的审稿人选,提取数据,并评估研究偏差,由于异质性而使用叙事综合.
主要成果:
- 与对照人群相比,ODD眼睛表现出更厚的视网膜神经纤维层 (RNFL) 和更差的基线平均偏差.
- 光学一致性断层扫描血管学 (OCTA) 揭示了特定部门的周周细胞血管面积密度降低.
- 伪毛囊炎的诊断测试显示出不同的产量,超声波和OCT表现最好;ODD在年轻的NAION患者中普遍存在.
结论:
- 多式成像证实了ODD的结构加厚,微血管稀疏和轻微的功能损失,通常进展缓慢.
- 协议化的多式成像工作流程在诊断疑似乳腺炎时优于单独的OCT.
- 在年轻的NAION中ODD的高患病率强调了其在风险分层和监测中的重要性.
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