营养在HPV感染和宫癌发展中的作用:保护性饮食因素的审查
Maria Guitian1, Gabriel Reina2,3, Silvia Carlos3,4
1School of Pharmacy and Nutrition, Universidad de Navarra, 31008 Pamplona, Spain.
饮食模式影响子宫癌 (CC) 风险. 特定的营养素和富含抗氧化剂的食物可能会降低人类乳头瘤病毒 (HPV) 的持久性,可能会降低CC的发展和进展.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 宫癌 (CC) 预防缺乏直接链接营养的确证据.
- 人类乳头瘤病毒 (HPV) 感染是CC的主要原因.
- 饮食因素在HPV感染和CC发展中的作用需要进一步调查.
研究的目的:
- 审查关于女性营养和HPV感染之间的关联的现有文献.
- 探索影响CC发病和进展的营养素,食物和饮食模式.
- 全球综合研究结果,重点关注低收入地区.
主要方法:
- 对营养,HPV和CC研究的系统文献综述.
- 纳入标准侧重于直接将饮食因素与CC相关的研究.
- 分析来自撒哈拉以南非洲,低收入国家和全球的数据.
主要成果:
- 有限的研究符合纳入标准,但建议饮食影响HPV易感性.
- 低叶酸摄入与显著更高的CIN3+病变风险相关 (OR 8.9).
- 增加维生素和抗氧化剂的摄入量与减少HPV持续性和CC进展有关.
结论:
- 饮食模式,特定营养素和富含抗氧化剂的食物可能会对HPV持久性和CC提供保护性益处.
- 营养是CC预防策略中可修改的因素.
- 建议采用整体方法,整合公共卫生,饮食和公平,以预防CC.
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