孟加拉国人类抗菌剂的使用:包括COVID-19大流行时代在内的五年趋势分析
S M Sabrina Yesmin1, Paritosh Chakma2, Umme Habiba2
1Directorate General of Drug Administration, Aushad Bhavan, Mohakhali, Dhaka 1212, Bangladesh.
Antibiotics (Basel, Switzerland)
|September 27, 2025
概括
孟加拉国在COVID-19期间抗菌药物的使用增加,具有广泛的抗菌谱.
科学领域:
- * * 公共卫生 公共卫生
- * 传染病 传染病
- * 药理学 药理学 药理学
背景情况:
- * 孟加拉国 (2019-2023) 抗微生物药物使用 (AMU) 的首个国家分析.
- *检查了两年趋势和COVID-19大流行对AMU的影响.
研究的目的:
- *分析孟加拉国国家抗菌药物消费模式.
- *评估COVID-19大流行对抗菌素处方的影响.
- *为抗微生物药物管理和打击抗微生物药物耐药性 (AMR) 的战略提供信息.
主要方法:
- *使用世卫组织解剖治疗化学物质 (ATC) 分类和每1000名居民每天定义的每日剂量 (DDD) 的抗菌药物使用 (AMU) 分析.
- *从制造商发送的抗微生物药物收集的数据.
- *根据世卫组织的获取,观察和储备 (AWaRe) 分类对抗微生物药物的分类.
主要成果:
- *AMU从2021-2022年增加到2023年减少. 塞菲克西姆和阿齐思罗米是最常被消费的.
- * 大多数使用的抗生素是广谱"观察"类药物 (50-67%口服,70-91%亲肠道).
- *在COVID-19大流行期间,AMU显著上升,特别是全身抗菌药物.
结论:
- *减少"观察"组抗生素的使用 (例如,cefixime,azithromycin) 对于实现2030年全球70%的"准入"抗生素使用目标至关重要.
- *加强管理计划和消除自我治疗是关键策略.
- * 调查结果为政策制定者提供了必要的数据,以解决孟加拉国AMR的问题.
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