ABxSG移动应用程序对抗生素处方的影响:一个中断的时间序列研究
Lai Wei Lee1, Shena Yun Chun Lim1, Yvonne Peijun Zhou1
1Division of Pharmacy, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.
Antibiotics (Basel, Switzerland)
|September 27, 2025
概括
一个移动应用程序,ABxSG,成功地减少了住院患者的抗生素使用,并改善了处方的适当性. 它使用行为设计思维开发,使医疗保健专业人员能够更好地管理抗微生物药物.
科学领域:
- 数字健康数字健康
- 抗微生物药物管理委员会
- 医疗信息学 医疗信息学
背景情况:
- 2021年新加坡总医院的高住院抗生素使用率 (48%).
- 需要通过可访问的信息来改善抗生素处方.
- 使用行为设计思维方法 (BDTA) 开发ABxSG移动应用程序.
研究的目的:
- 评估ABxSG对住院抗生素使用的影响.
- 评估抗生素适用性的变化.
- 测量药剂师主导干预的增加.
主要方法:
- 间断时间序列分析 (2021年10月 - 2024年9月).
- 对于ABxSG的18个发射前后数据点.
- 利用BDTA来提高用户体验和参与度.
主要成果:
- 立即减少了住院抗生素使用的1.66% (p < 0.01).
- 在18个月后持续减少3.12% (p < 0.01).
- 皮佩拉西林-塔扎巴克坦和塞夫特里亚克松的适当性得到改善;药剂师干预的增加.
结论:
- ABxSG有效地降低了住院患者的抗生素比例,并改善了处方.
- BDTA,领导力支持和战略规划推动了ABxSG的成功.
- 数字技术对于抗微生物药物管理和临床医生赋权至关重要.
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