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Updated: Jan 16, 2026

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FGF14衍生物不同调节 Nav1.2 和 Na 1.6 功能

Parsa Arman1, Zahra Haghighijoo1, Carmen A Lupascu2

  • 1Department of Pharmacology & Toxicology, University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555, USA.

Life (Basel, Switzerland)
|September 27, 2025
PubMed
概括

一种新型化合物ZL0177选择性调节电压通道 (Nav1.2和Nav1.6),为向治疗提供了潜力. 这项研究探讨了它对神经元刺激性和动作潜能释放的异型特异性影响.

关键词:
联邦政府基金14导航1.1.2 导航1.2 在线导航导航1.6 在线导航自动化平面补丁电生理学中枢神经系统 (CNS)发现药物的发现.蛋白蛋白相互作用 (PPI) 是一种蛋白蛋白相互作用.电压关闭的Na+通道 (Nav)

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