Dioscoreae Rhizoma对胃肠功能的影响:系统性审查
Ji-Hye Lee1, So-Young Park2, Min-Seok Jo1
1Department of Clinical Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Dioscoreae Rhizoma,或,显示出对胃肠道健康的承诺. 这次审查发现了人类和动物研究中改善肠道微生物群和减少炎症等益处的证据.
科学领域:
- 药理学和传统医学的医学.
- 胃肠病学 胃肠病学
- 营养学科学 营养学科学
背景情况:
- Dioscoreae Rhizoma () 在东亚传统上用于胃肠道健康.
- 本系统性审查评估了基于临床和体内研究的亚姆的胃肠道益处.
研究的目的:
- 系统地审查和综合证据,对 Dioscoreae Rhizoma 的胃肠道益处.
- 评估人类临床试验和体内实验研究中的发现.
主要方法:
- 在2025年4月之前,对8个数据库进行系统搜索.
- 包括人体和体内动物研究的Dioscoreae Rhizoma对胃肠功能的影响.
- 排除了体外研究,非原产品和多草药配方.
- 偏差风险评估使用诸如柯克兰偏差风险2 (RoB2) 等工具.
主要成果:
- 27项研究 (2人,25种动物) 符合纳入标准.
- 人类试验表明改善了肠道微生物群,血糖控制和术后恢复.
- 动物研究表明,减轻炎症,增强抗氧化剂防御,并保持粘膜完整性.
结论:
- 证据支持Dioscoreae Rhizoma通过免疫调节,抗氧化和微生物群调节的胃肠道益处.
- 限制包括缺乏高质量的人体研究和研究异质性.
- 需要进一步的严格研究来澄清机制并验证临床疗效.
更多相关视频
14:18Author Spotlight: Investigating the Potential of Chinese Herbal Medicinal Active Dioscin in Treating IgA Nephropathy
Published on: October 13, 2023
08:34Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation
Published on: July 27, 2022
相关概念视频
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents
Adsorbents...
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
Assessment of the Gastrointestinal System I: Subjective Data
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
Drugs Affecting GI Tract Motility: Other Laxatives
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
