在IBS中饮食修改导致症状,体重和脂质水平降低:两项随机临床试验
Bodil Roth1,2, Bodil Ohlsson1,2
1Department of Clinical Sciences, Lund University, 22100 Lund, Sweden.
减肥和饮食变化,如低FODMAP或低粉和低糖饮食 (SSRD),显著改善易肠综合征 (IBS) 症状和相关的体重/BMI. 超重/肥胖在IBS严重程度方面起着关键作用.
科学领域:
- 胃肠病学 胃肠病学
- 营养科学 营养科学
- 代谢健康 代谢健康
背景情况:
- 刺激性肠综合征 (IBS) 的特点是胃肠道和肠外症状.
- 超重/肥胖和代谢综合征在IBS患者中很常见.
- 低FODMAP和SSRD等饮食干预措施对于症状和体重管理是有效的.
研究的目的:
- 合并两个随机试验,研究营养干预对IBS的影响.
- 检查SSRD和低FODMAP饮食对IBS症状,体重,营养摄入量和脂质水平的影响.
- 为了测试减肥的假设,除了饮食成分,对于IBS的症状缓解至关重要.
主要方法:
- 合并了来自两项涉及260名IBS患者的随机试验的数据.
- 患者被分配给低粉和低糖饮食 (SSRD),低FODMAP饮食或控制饮食.
- 评估的症状问卷,食物摄入量,体重/BMI,以及在基线和干预后的脂质概况.
主要成果:
- 无论是SSRD还是低FODMAP饮食都减少了能量摄入,SSRD显示出更大的碳水化合物减少.
- 与对照组相比,SSRD和低FODMAP饮食显著减少了胃肠/肠外症状和体重/BMI.
- 体重/BMI降低与碳水化合物减少相关,并与症状改善有关;体重/BMI与脂质和症状更相关,而不是营养成分.
结论:
- 饮食干预 (SSRD,低FODMAP) 和减肥对于控制IBS症状至关重要.
- 超重/肥胖是IBS及其相关症状的发展和严重性的重要因素.
- 营养成分和体重管理策略应在IBS治疗计划中考虑.
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