孕产妇的叶酸补充,围产期因素和青春期前喘:健康成长研究的发现
Eva Karaglani1,2, Maria Michelle Papamichael3, Matzourana Argyropoulou1,2
1Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, 17671 Athens, Greece.
Nutrients
|September 27, 2025
概括
在怀孕后三个月,母亲补充叶酸与儿童喘风险的适度增加有关. 围产期和环境因素改变了这种关联,表明喘发育中的复杂相互作用.
科学领域:
- 儿科过敏和免疫学
- 围产期流行病学 围产期流行病学
- 环境健康 环境健康
背景情况:
- 叶酸在预防神经管缺陷方面的作用已确立,但其对儿科喘的影响尚不确定.
- 关于母亲的叶酸摄入量和儿童喘发展的证据有限.
- 调查围产期和环境修饰因子对于理解这种关联至关重要.
研究的目的:
- 为了检查母亲的叶酸补充剂和青春期前喘之间的联系.
- 确定改变这种关系的围产期和环境因素.
主要方法:
- 对2332名青春期前儿童进行横截面分析 (健康成长研究).
- 通过关于社会人口统计,围产和环境因素的问卷收集的数据.
- 后勤回归模型评估了母亲的叶酸摄入量 (按季度) 和喘患病率.
主要成果:
- 第三个月的叶酸补充与34%增加了青春期前喘的几率有关.
- 在早产婴儿和非吸烟母亲的婴儿中,观察到第二/第三季度补充剂增加了喘的几率.
- 第一季度补充剂与适合孕期婴儿的喘几率更高有关.
结论:
- 孕产妇摄入叶酸,特别是在怀孕晚期,显示与增加青春期前喘风险的温和关联.
- 围产期和环境因素显著改变了这一关联.
- 需要进一步研究叶酸补充剂的风险/益处,超出头三个月.
相关概念视频
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
972
Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
972
Asthma-I: Introduction
3.4K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.4K
Asthma: Pathogenesis and Management
1.2K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.2K
Asthma-IV: Diagnostic and Management
3.1K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.1K
Asthma-II: Pathophysiology and Classification
4.1K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.1K
Asthma-III: Symptoms and Complications
3.3K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
3.3K


