光学连贯性断层扫描-和光学连贯性断层扫描-在治疗中基于血管造影的评估-先天的非排泄性黄斑新血管化
Geun Young Moon1, Jong Seok Park1,2, Ki Woong Bae1,2
1Department of Ophthalmology, Nowon Eulji University Hospital, Seoul 01830, Republic of Korea.
Journal of clinical medicine
|September 27, 2025
概括
这项针对韩国患者非排泄性黄斑新血管化 (NE MNV) 的研究发现,年龄较大,中央黄斑厚度 (CMT) 更厚,NE MNV 尺寸更大是排泄性变化的危险因素. 建议对高风险的眼睛进行频繁的监测.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 与年龄相关的斑点退化症
背景情况:
- 非排泄性黄斑新血管化 (NE MNV) 是与年龄相关的黄斑退化 (AMD) 中排泄性变化的前体.
- 了解NE MNV进展的自然过程和风险因素对于及时干预至关重要.
研究的目的:
- 评估韩国患者治疗前的NE MNV的临床特征和自然过程.
- 确定与NE MNV向排泄性变化的进展相关的重大风险因素.
主要方法:
- 对21名韩国患者的21只眼睛进行了回顾性纵向研究,这些患者患有NE MNV.
- 图表审查包括最佳校正的视敏度 (BCVA),光学连贯性断层扫描 (OCT) 和OCT血管学.
- 考克斯的比例危险分析被用来确定排泄性转换的风险因素.
主要成果:
- 平均随访时间为15.1个月,66.7%的眼睛出现了排泄性变化.
- 较高的年龄 (HR: 1.096),较大的基线中央黄斑厚度 (CMT) (HR: 1.025),以及较大的基线NE MNV大小 (HR: 1.618) 是显著的风险因素.
- 基线BCVA为0.15±0.18 logMAR;基线CMT为265.3±37.1微米.
结论:
- 在NE MNV中排泄性转换的显著风险因素包括晚年,基线CMT增加和基线NE MNV更大.
- 建议对NE MNV患者进行更频繁的监测,并确定了风险因素,以促进及时管理.
- 这项研究提供了对韩国人口中NE MNV进展的见解.
相关概念视频
Open Angle Glaucoma: Treatment
963
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
963
Angle Closure Glaucoma: Treatment
1.2K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.2K
Glaucoma: Overview
1.2K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.2K
Imaging Studies VII: Vascular Imaging
312
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
312


