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颠倒式下垂体膜内皮质角质形成的治疗结果

Karolina Bonińska^1,2, Sławomir Cisiecki^1,2,3, Tomasz Dybek²

¹Centrum Medyczne "Julianów", ul. Żeglarska 4, 91-321 Łódź, Poland.

Journal of clinical medicine

|September 27, 2025

概括

颠倒的Descemet膜内皮质角质成形 (DMEK) 移植可以通过手术内光学连贯断层扫描 (iOCT) 进行管理. 即使在33天后,重新定位错误放置的DMEK移植,也可以带来有利的视觉结果.

科学领域:

眼科医生眼科眼科
角膜外科手术角膜外科手术
医疗技术医疗技术医学技术

背景情况:

费克斯内皮角膜损伤 (FECD) 需要角膜移植以恢复视力.
德斯梅特膜内皮质角质整形 (DMEK) 是一种先进的内皮质角质整形技术.
在眼科手术过程中,手术内光学连贯性断层扫描 (iOCT) 可提供实时可视化.

研究的目的:

介绍一个颠倒的Descemet膜内皮质角质成形 (DMEK) 移植的管理.
在DMEK手术中证明手术内光学连贯性断层扫描 (iOCT) 的实用性.
在低于最佳的DMEK放置的情况下,评估移植重定位的结果.

主要方法:

一个74岁的女性FECD接受DMEK的病例报告.
使用iOCT进行手术期间的移植位置评估,没有手术前的标记.
由于没有改善,在初级手术后33天进行了移植重定位.

主要成果:

术后初始视力敏度和角膜厚度表明移植位置不当.
在重新定位后,中角膜厚度从708微米提高到495微米.
最终纠正距离视敏度 (CDVA) 在18个月后改善到20/40未纠正 (sc).

结论:

在没有术后改善的DMEK病例中,考虑移植错位.
在DMEK手术中的学习曲线可以影响并发症率.
逆向DMEK的移植重定位提供了有利的预后,即使延迟.

关键词:

德塞梅特膜内皮细胞内皮质塑.福克斯内皮角膜缩症角膜缩症体内皮层的角质塑性.内部操作的OCT-OCT 颠倒倒的植入方式

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