左心室质量指数和心房体积指数增加与心房动患者的心房纤维化有关
Simona Manole1,2, Roxana Pintican2, Claudia Budurea1
1IMOGEN Research Institute, County Clinical Emergency Hospital, 400006 Cluj-Napoca, Romania.
Journal of clinical medicine
|September 27, 2025
概括
通过心声学测量的左心房体积与身体表面积 (LAVi) 进行索引,可以帮助识别心房动 (AF) 患者的心房纤维化. 这种成像参数对诊断AF患者心脏纤维化有前途.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 生物医学工程 生物医学工程
背景情况:
- 心房纤维化是心房动 (AF) 的关键病理特征.
- 需要使用非侵入性成像方法来评估AF患者心房纤维化.
- 心声学参数可能与心房纤维化存在相关.
研究的目的:
- 在患有AF的患者中识别与心房纤维化相关的心声谱衍生成像参数.
- 为了评估诊断性能,将左心房体积与身体表面积 (LAVi) 进行索引,以检测心房纤维化.
主要方法:
- 一项前性横截面观察性研究,包括112名参与者 (29名有纤维化的AF,37名没有纤维化的AF,46名对照).
- 参与者接受了临床评估,心声学和心脏MRI.
- 分析重点是心声回声学衍生的参数,特别是LAVi和LVMi,以及它们与MRI确认的LA纤维化相关.
主要成果:
- 身体表面积指数的左心房体积 (LAVi) 与AF患者的LA纤维化有显著的相关性 (AUC 0.69).
- 最佳的LAVi切线为42.7毫升/平方米,用于检测LA纤维化,其灵敏度为88.46%,特异性为41.67%.
- 按身体表面积指数的左心室质量 (LVMi) 也与LA纤维化有关,最佳切断值为140.2g/m2.
结论:
- 索引为BSA的左心房体积 (LAVi) 是确定AF患者心脏纤维化的有前途的心声学参数.
- 测量LAVi可能有助于非侵入性评估和诊断心房纤维化,可能指导治疗策略.
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