CAPTURE和PUMA作为COPD风险患者的病例发现工具 - 一个多中心的墨西哥体验
Arturo Cortes-Telles1, Ismael Juarez-de-Dios2, Esperanza Figueroa-Hurtado1
1Clinica de Enfermedades Respiratorias, Hospital Regional de Alta Especialidad de la Peninsula de Yucatan IMSS-Bienestar, Merida 97130, Mexico.
Journal of clinical medicine
|September 27, 2025
概括
这项研究评估了在墨西哥查慢性阻塞性肺病 (COPD) 的PUMA和CAPTURE问卷. 这两种工具在识别有COPD螺旋测量证据的患者时都显示出中等的准确性.
科学领域:
- 肺部病理学 肺部病理学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 慢性阻塞性肺病 (COPD) 构成了全球重大健康负担.
- 低收入和中等收入国家普遍存在低诊断,原因是有限的螺旋计获取.
- 在常规的临床实践中,需要有效的病例发现策略.
研究的目的:
- 为了比较PUMA和CAPTURE问卷对墨西哥成年人COPD查的有效性.
- 评估这些问卷在识别螺旋计阻塞模式时的敏感性和特异性.
- 评估问卷得分与FEV1/FVC比率的相关性.
主要方法:
- 一项涉及COPD查活动的多中心,横截面研究.
- 40岁以上有风险因素 (吸烟,生物质暴露) 的成年人被纳入.
- 经过支气管扩展后的FEV1/FVC<0.70证实了COPD诊断;分析了敏感度,特异性和ROC曲线.
主要成果:
- 在197名参与者中,37.1%的人被诊断出COPD.
- 普马问卷获得了74.0%的灵敏度和51.6%的特异性 (切断值≥6).
- CAPTURE问卷显示了不同的结果:≥3 (76.9%的灵敏度,40.9%的特异性) 或≥4 (61.5%的灵敏度,72.7%的特异性).
- 这两个问卷表都显示了中等准确性 (Puma的ROC为0.693,Capture的ROC为0.714) 和与FEV1/FVC的显著负相关性.
结论:
- 在墨西哥人口中,PUMA和CAPTURE问卷提供了适度的确定性来诊断患有COPD风险的患者.
- 这些工具可以帮助识别初级保健机构中的风险人群.
- 需要在不同的群体中进一步验证.
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