最佳睡眠开始时间和持续时间对中风风险的影响:一个基于社区的跨部门研究
Junyi Ma1, Yang Wang2, Ji Zhang1
1Department of Neurology, Xiangya Hospital, Central South University, Nanchang 330006, China.
Journal of clinical medicine
|September 27, 2025
概括
最佳的睡眠时间和发病时间显著影响中风风险. 实现6-8小时的睡眠,最好是在晚上10点到11点之间开始,对于大脑血管保护至关重要.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 睡眠时间和中风风险之间确立的联系.
- 对睡眠开始时间和持续时间对中风亚型的综合影响的理解有限.
- 循环生物学表明,睡眠时间影响血管风险,无论持续时间如何.
研究的目的:
- 量化睡眠开始时间和持续时间对中风风险的共同贡献.
- 为了确定大脑血管健康的保护性睡眠概况.
- 探索睡眠参数和中风亚型之间的相互作用.
主要方法:
- 基于人口的横截面研究.
- 招募了8168例缺血性中风病例,3172例脑内出血病例和13458例对照病例.
- 使用标准化计算机辅助采访来收集睡眠参数和联合分析.
主要成果:
- 睡眠时间短 (<6小时) 在所有睡眠开始时间都持续增加缺血性中风风险.
- 晚上10点到12点之间开始的最佳睡眠时间 (6-8小时) 与缺血风险最低相关.
- 长时间睡眠 (>8小时) 早期发病 (晚上10点以下) 增加了风险,而晚期发病 (晚上11点至早上12点) 是保护性的;在脑内出血中观察到类似的趋势.
结论:
- 睡眠时间和发病时间相互作用,影响整体中风风险.
- 最佳的脑血管保护包括至少6个小时的睡眠,最好是在晚上10点到11点之间开始.
- 睡眠优化在高风险人群中为预防中风提供了一个潜在的可修改的目标.
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