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Updated: Jan 16, 2026

Controlled Odor Mimic Permeation Systems for Olfactory Training and Field Testing

Controlled Odor Mimic Permeation Systems for Olfactory Training and Field Testing

Published on: January 28, 2021

后COVID-19嗅觉功能障碍的嗅觉训练:对效率和组合疗法的元分析

Ali Alsuheel Asseri¹, Mona Aldukain², Ali Aldukain²

¹Department of Child Health, College of Medicine, King Khalid University, Abha 62521, Saudi Arabia.

Journal of clinical medicine

|September 27, 2025

概括

嗅觉训练 (OT) 有效地治疗COVID-19后的嗅觉功能障碍. 将OT与PEA-luteolin等疗法结合起来,可以提高嗅觉缺陷的恢复结果.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
神经学神经学
传染性疾病传染性疾病

背景情况:

后COVID-19嗅觉功能障碍是SARS-CoV-2感染的常见后果.
正在研究标准化嗅觉训练 (OT) 协议的有效性.
需要系统地评估OT的有效性与各种比较器.

研究的目的:

系统地审查和元分析嗅觉训练 (OT) 对COVID-19后嗅觉功能障碍的有效性.
将OT与没有治疗,安慰剂或替代疗法进行比较.
通过验证的气味测试来评估嗅觉功能的改善.

主要方法:

在PubMed,Web of Science和Ovid Medline的系统文献搜索到2025年2月.
包括八个随机对照试验 (RCT),遵循PRISMA指南.
使用RevMan和Open Meta-Analyst进行的元分析,具有偏差评估风险.

主要成果:

与对照组相比,嗅觉训练显著改善了嗅觉得分.
与PEA-luteolin的联合治疗显示出最大的改善 (MD = 4.62).
组合疗法与更高的康复率有关 (RR = 1.65).

结论:

嗅觉训练是COVID-19后嗅觉功能障碍的有效治疗方法.
辅助疗法,特别是PEA-luteolin,可以促进恢复.
建议进一步进行大规模的标准化RCT,以优化治疗方案.

关键词:

组合疗法组合疗法这是一个元分析.嗅觉功能障碍嗅觉功能障碍嗅觉训练是通过嗅觉训练进行的.在COVID-19后的时间里.

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