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减肥后体重减轻的性别差异 减肥后体重减轻的性别差异
Santo Colosimo1, Federica Sileo1,2, Andrea Gambetti3
1Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, 20133 Milan, Italy.
Journal of clinical medicine
|September 27, 2025
概括
在袖子胃切除术后,男性获得了更大的绝对减肥,但相对减肥在两性之间是相似的. 这凸显了代谢腹腔外科手术 (MBS) 获取和结果的潜在性别差异.
科学领域:
- 腹部外科 腹部外科
- 肥胖医学 肥胖医学
- 性别健康差异 性别健康差异
背景情况:
- 代谢 - 减肥手术 (MBS) 对严重肥胖有效,但性别差异影响了获取和结果.
- 男性的基线体重和并发病率较高,但在MBS中代表性较低.
- 关于性别特异性结果的证据,特别是在地中海人群中,需要澄清.
研究的目的:
- 在意大利队列中评估袖子胃切除术后减肥的性别差异.
- 根据当前的多学科协议评估结果.
- 为提供公平的外科手术和术后护理提供信息.
主要方法:
- 对131名 (22名男性,109名女性) 接受袖子胃切除术的患者进行前性观察研究.
- 在基线和12个月评估人体测量和代谢参数.
- 使用t测试和回归模型比较绝对减肥,总减肥百分比 (TWL%),超重减肥百分比 (EWL%) 和腰围.
主要成果:
- 在12个月内,男性的绝对体重减轻 (-36.6公斤) 比女性 (-31.2公斤) 显著增加 (p=0.028).
- 在TWL%,EWL%或腰围缩小方面没有发现显著的性别差异.
- 性别预测绝对减肥,但不是比例减肥;两种性别都达到类似的临床显著减肥值.
结论:
- 男人经历了更大的绝对体重减轻,但相对体重减轻在袖子胃切除术后的性别之间是可比的.
- 在使用MBS方面,性别差异仍然存在.
- 研究结果强调,需要在减肥手术中提供公平的准入和个性化的术后护理.
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