牙周炎症是否与肝硬化有关? 一个横截面研究
Goran Rinčić1, Marija Roguljić2, Nives Rinčić3
1Sestre Milosrdnice University Hospital Centre, Division of Hematology, Department of Internal Medicine, University of Zagreb School of Dental Medicine, 10000 Zagreb, Croatia.
Journal of clinical medicine
|September 27, 2025
概括
牙周炎是一种严重的牙疾病,在肝硬化患者中明显更为普遍. 这表明牙周健康不良和晚期肝病之间存在强烈联系,突显了综合护理的必要性.
科学领域:
- 口腔健康 口腔健康
- 肝病学 肝病学是一种肝病学.
- 系统性疾病 系统性疾病
背景情况:
- 牙周炎越来越多地被认为与全身性非传染性疾病有关.
- 肝脏疾病,包括肝硬化 (LC),已与口腔健康状况有关.
- 在LC患者中调查牙周状况对于了解疾病并发症至关重要.
研究的目的:
- 为了确定牙周健康状况和肝硬化 (LC) 之间的关联.
- 评估LC和没有LC的患者的临床牙周参数.
- 为了确定LC的预测因素,包括牙周因子.
主要方法:
- 从内部医学中招募了100名患者 (50名LC病例,50名对照).
- 使用探针出血 (BoP),探针口袋深度 (PPD),牙衰退 (GR),临床附着水平 (CAL) 和牙周炎症表面积 (PISA) 评分来评估牙周健康.
- 利用分步后勤回归来确定LC的预测因素,并纳入牙周状况.
主要成果:
- 在LC组表现出明显更糟糕的牙周参数和牙周炎的更高的流行率 (p = 0.012).
- 92%的LC患者患有严重的牙周炎 (III和IV阶段).
- 酒精消费 (OR = 23.81) 和PISA评分 (OR = 1.006) 是LC的独立预测因素.
结论:
- 在肝硬化组中观察到牙周病的患病率更高.
- 这些发现表明肝硬化和牙周炎之间存在显著的关联.
- 牙周健康评估在治疗肝病患者方面可能是有价值的.
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