在过去十年中,在美国的成年人中活跃吸烟的患病率和趋势:人口层面的分析
Mohammad Alabbas1, Jingyi Shi2, Yuqi Guo3,4
1Department of Gastroenterology, Hepatology and Nutrition, Cleveland Clinic, Cleveland, OH 44195, USA.
Journal of clinical medicine
|September 27, 2025
概括
在美国,C型肝炎 (HCV) 的成年人中,吸烟仍然非常普遍,过去十年来,吸烟率停滞不前. 这种持续的吸烟会增加这种脆弱人群中肝硬化和癌症的风险.
科学领域:
- 公共卫生 公共卫生
- 肝病学 肝病学是一种肝病学.
- 成 药物 药物 药物 药物
背景情况:
- 吸烟显著增加了肝硬化和肝细胞癌的风险,在患有型肝炎病毒 (HCV) 感染的患者.
- 了解吸烟的流行率和趋势对于减轻与HCV相关的肝病进展至关重要.
研究的目的:
- 确定过去十年 (2007-2018年) 美国HCV成年人中活跃吸烟的流行率.
- 分析这个群体中活跃吸烟的时间趋势.
- 确定与HCV患者活跃吸烟相关的人口和临床因素.
主要方法:
- 从2007-2018年国家健康和营养检查调查 (NHANES) 中重复的横截面数据的分析.
- 纳入标准:美国成年人 (≥20岁) 具有血清学证据的HCV和完整的吸烟数据.
- 统计方法包括线性回归,趋势分析的结点回归和因子识别的调查加权多变量后勤回归.
主要成果:
- 在患有HCV的成年人中,活跃吸烟的累积患病率为56.4% (95% CI,49.2-63.4).
- 在研究期间,没有观察到吸烟患病率的统计学上显著的线性趋势 (p = 0.93).
- 与更高的吸烟率相关的因素包括女性性别,低收入,吸毒和抑郁症. 较低的几率与高等教育,肥胖和频繁的医疗保健访问有关.
结论:
- 活跃吸烟非常普遍,在美国成年HCV人口中似乎是流行病.
- 在过去的十年中,吸烟率仍然令人担忧地高,并且处于停滞状态.
- 这种持续高的吸烟患病率对未来与HCV相关的肝硬化和肝细胞癌的增加构成重大风险.
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