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V1-R波的幅度预测了跨导管大动脉替换后的生存率

Orhan Ince¹, Esra Donmez¹, Sevgi Ozcan¹

¹Department of Cardiology, Bagcilar Training and Research Hospital, Istanbul 34200, Turkey.

Medicina (Kaunas, Lithuania)

|September 27, 2025

概括

术前心电图V1-R波幅和肺动脉压力预测透气管大动脉置换 (TAVR) 后的一年死亡率. 升高的V1-R波幅和缩性肺动脉压力与TAVR后的死亡风险增加有关.

科学领域:

心脏病学心脏病学
心脏外科手术心脏外科手术
医学诊断医学诊断医学诊断

背景情况:

右心脏功能和肺动脉压力对于通过导管的大动脉置换 (TAVR) 后的结果至关重要.
肺动脉压力通常使用侵入性方法或心声回声仪进行评估.
肺动脉压的非侵入性指标可以改善TAVR前风险分层.

研究的目的:

研究V1-R波幅在心电图上作为肺动脉压力的非侵入性预测器.
确定手术前V1-R波幅和心性肺动脉压与TAVR后一年死亡率之间的关联.
确定接受TAVR的患者死亡率的独立预测因素.

主要方法:

对236名患有严重症状性大动脉狭窄症的患者进行了回顾性单中心研究,这些患者接受了TAVR.
在手术前分析V1-R波幅 (心电图) 和静脉肺动脉压力 (心声图).
在TAVR后的一年内,幸存者和非幸存者之间的结果比较.

主要成果:

一个V1-R波幅切线为66.5μV显示了66.1%的灵敏度和66.7%的特异性来预测一年死亡率 (AUC:0.735).
系统性肺动脉压 (sPAP) ≥55.5mmHg具有67.9%的灵敏度和68.3%的特异性 (AUC:0.708).
死亡率增加的独立预测因素包括脑血管疾病,高sPAP和高V1-R波幅;他类药物使用预测死亡率降低.

结论:

在手术前的V1-R波幅和缩性肺动脉压是TAVR后的一年死亡率的独立预测指标.
这些发现强调了在TAVR之前评估右心功能的重要性.
V1-R波幅为肺动脉压力和死亡风险分层提供了潜在的非侵入性标记.

关键词:

在V1-R波的波幅幅度.死亡率死亡率缩性肺动脉的压力压力通过导管更换大动脉门.

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