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Updated: Jan 16, 2026

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关于昆利丁-3-one BisQACs的结构-功能洞察:合成,细菌耐药性的调制,结构-活性关系和生物分析

Antonio Sabljić1,2, Doris Čarija1, Alma Ramić3

  • 1Department of Chemistry, Faculty of Science, University of Split, R. Bošković 33, 21000 Split, Croatia.

Pharmaceuticals (Basel, Switzerland)
|September 27, 2025
PubMed
概括

基于素的新型双四级化合物 (bisQACs) 对抗性细菌具有强大的抗微生物活性. 这些新药物破坏细菌膜,减少生物膜的形成,为下一代抗生素具有较低的抗药性潜力提供了一个有希望的途径.

关键词:
抗微生物耐药性 抗微生物耐药性生物膜抑制抑制的作用二次方位化合物 (bisQACs) 是一种二次方位化合物.细胞毒性 细胞毒性膜透气化 膜透气化分子对接的分子对接.

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