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Updated: Jan 16, 2026

Screening Traditional Chinese Medicine Compounds for Inhibiting UCHL3 Activity Based on Molecular Docking and Deubiquitinating Enzyme Probe Technology
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使用HCAR3进行结构建模和虚拟查,以发现潜在的治疗分子.

Yulan Liu1, Yunlu Peng1, Zhihao Zhao1

  • 1Kobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong-Shenzhen, Shenzhen 518172, China.

Pharmaceuticals (Basel, Switzerland)
|September 27, 2025
PubMed
概括

研究人员确定了六种新型化合物,这些化合物与氧碳酸受体3 (HCAR3) 结合,这是治疗失脂症的关键标. 这些潜在的候选药物显示出有前途的结合亲缘关系,为脂质调节疗法提供了新的途径.

关键词:
氧碳酸受体3 3 氧碳酸受体分子动力学模拟,分子动力学模拟虚拟选是虚拟的选.

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